In medical billing, modifiers are equally important as billing codes. They resemble codes, but they function differently and play a crucial role in billing tasks. Modifiers are specific numbers that indicate the details of services performed on patients. When billers use them correctly, claim denials decrease and financial stability increases. However, improper use can trigger claim rejections and even audits. If you want expert help getting them right, specialized orthopedic billing services can make a real difference.
In case you’re wondering what are orthopedic billing guidelines, they define how medical billers should apply codes and modifiers in compliance with payer rules. Understanding these guidelines ensures accurate claims, minimizes rejections, and helps maintain regulatory compliance. Partnering with experts who follow these principles ensures your claims are clean, compliant, and paid faster—while freeing your staff to focus on patient care.
In this article, we will discuss the role and importance of orthopedic billing modifiers. We will also discuss the best practices to use them in your daily billing routine. Moreover, we will suggest a professional billing agency, SysMD, for using modifiers accurately in your billing systems.
Importance of Orthopedic Billing Modifiers

A billing modifier is a two-character code (numeric or alphanumeric). Usually, it is present in addition to a CPT or HCPCS code on bills and claims. This unique code provides extra details about the services provided to patients. If billers do not use these modifiers when needed, the claim will be considered incorrect.
Orthopedic billing modifiers come in many types, and each modifier has its specific purpose. These modifiers are not used in every bill but are used in special circumstances. For example, these codes show
- that a surgery is on the left or right knee
- that a procedure occurred in more than one session
- that one service is separate from another procedure
- that a procedure was performed by one or more surgeons
Also, correct modifier usage ensures compliance with CMS, NCCI edits, and specific payer rules.
Major Modifiers in Orthopedic Medical Billing

As we know, CPT and ICD-10 codes in orthopedic billing show the details and medical necessity of the service, respectively. Then why are modifiers necessary to use? They are necessary because they cover details of the service that are absent in the main codes, such as whether two services are separate.
Sometimes, due to a heavy workload, billers use only codes and neglect the modifiers. Ultimately, it can lead to rejection of claims and loss of revenue. That is why you should know all essential orthopedic billing modifiers to streamline your billing tasks.
Let us discuss some major modifiers of routine orthopedic medical billing.
Modifier -59: Distinct Procedural Service
Modifier -59 is one of the most used and most audited modifiers. It tells the payer that two procedures, normally bundled together, were actually different. For example, if a physician performs a fracture repair and a joint injection during the same session, these are separate services. In this case, modifier -59 will show that these two services are separate and will be billed separately. Both services will not be bundled under one payment.
When you use this modifier, keep some points in mind:
- Use only when services are truly separate.
- Do not use it to bypass NCCI edits without justification.
- Documentation must clearly show why the procedures were different.
Modifier -25: Significant, Separately Identifiable E/M Service
Billers use modifier -25 when physicians perform evaluation and management (E/M) service on the same day as a procedure. For example, a patient visits the orthopedic department for knee pain. The physician evaluates the problem and performs an injection. Now, the E/M service is before and after the procedure. In this case, modifier -25 must be added to the E/M code.
When you use this modifier, keep some points in mind:
- Use only if the service performed after the evaluation was necessary and separate.
- Do not use when the E/M is routine or related only to the procedure itself.
Modifier -RT and -LT: Laterality
Many orthopedic codes do not show the exact side or laterality of the surgery. In this case, modifiers -RT and -LT show the right side and left side of the treatment, respectively. Thus, these codes prevent confusion and lead to claim acceptance. For example,
- Total knee replacement on the right side → CPT code with modifier -RT
- Shoulder arthroscopy on the left side → CPT code with modifier -LT
Modifier -50: Bilateral Procedure
Sometimes, patients get the procedure on both sides of the body. How will you mention it on the bills? Obviously, with the help of modifier -50 to show a bilateral procedure. For instance, if a physician performs carpal tunnel release on both wrists during the same session, modifier -50 applies.
When you use this modifier, keep some points in mind:
- Check the payer guidelines before assigning this modifier. Some payers demand a single modifier (-50), and some want separate modifiers (-RT and -LT). So, assign according to the requirements.
- Documentation must show proof of bilateral service.
Modifier -22: Increased Procedural Service
This modifier shows the extra time, effort, and work of a physician on the patient. It truly acts as a bonus in physician payment. For example, a surgeon treats a severely complicated fracture that needs a longer operative time and extra work. In this case, billers will use modifier -22 to request higher reimbursement.
When you use this modifier, keep some points in mind:
- Documentation should explain and show why the procedure needed more time and work.
- Payers can request operative notes before processing payment.
Modifier -24: Unrelated E/M Service During Post-Op Period
Some orthopedic surgeries involve long global periods. If a patient returns during that period with a problem that is not related to the surgery, modifier -24 applies.
For example:
A patient has shoulder surgery. After two weeks, the same patient comes in for another issue, such as an ankle sprain. The E/M for the ankle sprain must include modifier -24.
Modifier -57: Decision for Surgery
In orthopedic billing modifiers, -57 indicates when surgeons make a sudden decision for surgery during evaluation and management (E/M). A patient comes in with a fracture. The physician evaluates and decides that they need surgery immediately. The E/M visit should include modifier -57. This modifier shows that billers should not bundle the surgery with E/M, as the decision was essential for the patient’s treatment.
Modifiers -76 and -77: Repeat Procedures
In hospitals, many services such as medical tests and injections are needed repeatedly. In this case, modifiers -76 and -77 clarify why the service appears more than once. The clear role of these modifiers is:
- -76: Repeat procedure by the same physician
- -77: Repeat procedure by another physician
Modifier -X{EPSU}: Subset Modifiers for -59

CMS introduced the X-modifiers as a more precise replacement for -59. They are:
- XE – Separate encounter
- XS – Separate structure
- XP – Separate practitioner
- XU – Unusual non-overlapping service
Although -59 is still accepted, some payers prefer the X-modifiers for more detail.
How Does Choosing the Right Partner Affect Billing?
Want to incorporate correct orthopedic billing modifiers in your billing routine? Hire SysMD’s team because they have experienced billing staff to handle all the complexities of modifiers. They specialize in helping orthopedic practices maximize revenue with accurate billing and coding support.
Our expert team understands the complexities of orthopedic billing modifiers, payer-specific rules, and compliance requirements. By partnering with us, your practice can reduce denials, streamline reimbursements, and focus more on patient care while we handle the billing challenges.
Conclusion
In short, orthopedic billing modifiers play an important role in ensuring accuracy. Essential modifiers like -59, -25, -RT, -LT, and others clarify services, prevent denials, and ensure compliance with CMS, payer rules, and NCCI edits.
By applying the right modifiers with proper documentation, you can improve revenue cycles and avoid compliance risks. For expert support, partnering with professionals like SysMD ensures your billing process remains efficient, accurate, and profitable.
FAQs
What are orthopedic billing modifiers?
They are two-character codes that give extra details about procedures, such as laterality, separate services, or repeated work.
Why is modifier -59 important in orthopedics?
It prevents payers from bundling services that are truly separate, ensuring full reimbursement.
What is the difference between -RT/-LT and -50?
-RT and -LT specify right or left side. Modifier -50 indicates the procedure was bilateral.
Can I use modifier -25 for every visit with a procedure?
No. Use it only when the E/M service is significant and separately identifiable from the procedure.
What happens if modifiers are used incorrectly?
Improper use can cause claim denials, payment delays, or even compliance audits.